Welcome to your July newsletter.
June has been a funny old month, the club off topic section has been very busy, whereas the psoriasis threads and members joining has hit a low ... hopefully it's just a temporary covid induced blip and we will see an increase in activity in the health boards in the coming months.
I guess with lots of countries easing the covid-19 restrictions in July normality will hopefully begin to return, and as we are nervously starting to get out and about and trying to stay safe we will begin to see what the new normal looks like .... it would be interesting to hear if any of our members have actually had covid-19 and if so it would be good to hear how you coped with it, if you have a covid story come and tell us here Covid-19 aka corona virus and psoriasis
I would like to take this opportunity to thank KatT for taking over the music column from Fred who had been doing it from the start and needed to be spending his time on more pressing matters. So thank you KatT, I hope we will all support her by sending recommendations and trying to solve the quiz
If you have a thread about your experiences what better time to come in and update your thread or if you don't have one and would like to start a thread about your treatment you can do that Here .
The off topic has been as busy as ever as we now have a games and quiz board where many of the existing games have been moved to and a few new ones added. Why not pop in and have a look Games and Quizzes Here
If you're a guest feel free to browse through the links here and join if you want to see more. Some off topic items may not be available for guests but all the health boards are
The forum team have been busy keeping an eye on the Club and are there for you, so if you can't find something you are looking for or if you aren't sure how to do something, we are here to help just click the link below to make contact HERE
If you are currently a subscriber to the newsletter you will receive notification with a link at the beginning of each month. If you don't currently recieve one and would like to receive an email when a new newsletter is made click HERE
Note: Subscribed members get an early view of the newsletter.
Hello, thought I would check out a forum as I am starting a new med.
First I will recap my journey to this point:
I was diagnosed as having Psoriatic arthritis around 1992.
I was told that by the time I was 55 I would be in a wheelchair. I took just about everything imaginable between then and 1998. Methotrexate, sulfa, don't even remember it all. Nothing made any difference.
In 1998 I was ready to give up and my primary care Dr recommended a hand specialist in the area that had done surgery on people from all over. I told him I was at the end of my rope. He said “There’s a new med out called enbrel, let’s try that”. I started enbrel and it saved my life. A miracle drug.
In 2011 we moved to mexico. I stopped the enbrel as my insurance would not cover it there. It took several years for it to wear off. When it did both the psoriasis and arthritis came back with a vengance. Click here to read more
To read more or to start a thread about your treatment or update your own ........... Click here
Rinvoq goes for psoriatic arthritis approval
AbbVie today announced that it has submitted applications for a new indication to the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) for RINVOQ (upadacitinib; 15 mg, once daily), a selective and reversible JAK inhibitor, for the treatment of adult patients with active psoriatic arthritis.
"Psoriatic arthritis is a complex heterogeneous disease with manifestations across multiple domains, including joints and skin, causing daily pain, fatigue and stiffness," said Michael Severino, M.D., vice chairman and president, AbbVie. "We look forward to working with regulatory authorities and hope to bring RINVOQ to people living with this debilitating disease as quickly as possible.". read more here
Taltz v Humira in psoriatic arthritis study
Eli Lilly shared new results from a subgroup analysis of the Phase 3b/4, 52-week Head-to-Head study of Taltz (ixekizumab) versus Humira (adalimumab) in biologic-naïve patients with active psoriatic arthritis (PsA)
Eli Lilly and Company shared new results today from a subgroup analysis of the Phase 3b/4, 52-week SPIRIT-Head-to-Head (SPIRIT-H2H) study of Taltz versus Humira (adalimumab) in biologic-naïve patients with active psoriatic arthritis (PsA). SPIRIT-H2H was the first superiority study versus Humira in PsA with a primary endpoint of simultaneous achievement of ACR50 (at least 50% improvement in disease activity as defined by the American College of Rheumatology) and PASI 100 (100% improvement in the Psoriasis Area and Severity Index) at Week 24.
In this prespecified analysis, efficacy outcomes through Week 52 were compared between Taltz and Humira in subgroups of patients on monotherapy, concomitant methotrexate (MTX), or concomitant MTX along with an additional conventional synthetic disease-modifying antirheumatic drug (csDMARD), including sulfasalazine, cyclosporine, or leflunomide. Results at 52 weeks showed improvements were seen with Taltz across multiple endpoints, with or without the use of MTX or other csDMARDs. read more here
Affibody shows data from phase 2 trial of ABY-035 for Psoriasis
Affibody Announces Positive Top-Line Data from Phase 2 Proof-of-Concept Trial of ABY-035 in Psoriasis
Affibody, a clinical stage biopharmaceutical company, today announced positive top-line data from its 52-week trial investigating the novel bispecific IL-17A inhibitor ABY-035 in patients with moderate-to-severe psoriasis (“AFFIRM-35”).
The primary endpoint of the Phase 2 AFFIRM-35 double-blind, placebo controlled, 52-week Phase 2 proof-of-concept trial was PASI 90 response defined as an at least 90% improvement of the baseline Psoriasis Area Severity Index (PASI) score after 12 weeks of treatment. In the group that finished the 80 mg Q2W induction period 15 out of 17 patients (88%) achieved a PASI 90 response and 10 out of 17 patients (59%) achieved complete or almost complete disease remission with an absolute PASI of 1 or below. The overall PASI 90 response at week 12 was 71% for all 21 subjects randomized to the 80 mg Q2W group.
Over one year, 17 out of 21 (81%) subjects in the 80 mg Q2W induction group and 18 out of 22 (82%) subjects in the 160 mg Q2W induction group achieved an absolute PASI of 1 or below and in general maintained a complete or almost complete disease remission with once monthly dosing. The majority of reported adverse events were mild and resolved during treatment. Overall, ABY-035 treatment appeared tolerable and safe.
“Our Phase 2 AFFIRM-35 trial in patients with moderate-to-severe psoriasis has shown excellent and sustained clinical response in patients. Most patients are continuing ABY-035 treatment in an ongoing open label extension study. Based on these promising results, we believe that ABY-035 has best-in-class potential for auto-immune diseases,” said David Bejker, CEO of Affibody. “The patient centric design has also enabled us to comfortably select doses for further development”. Read more here
Turnedlight has updated her poll thread "Weight gain on Biologics"
This is an interesting question and if you haven't already voted in the thread just click the link here to cast your vote Go here to vote
jiml has updated his thread "jims journey on Skilarence"
I had a blood test yesterday my first since the beginning of March my doctor has just phoned to give the results which were all within the normal ranges and the lymphocyte count which was 1.07. So a much longer period and no real change from March when the lymphocyte count was 1.15 still no sign of psoriasis returning and the arthritis is virtually gone from my shoulders which kept me awake at night with discomfort and are now back to normal Going to stick to 5 tablets a day as that seems to be the level Read more here
A lot of members only threads and journals have been updated, come and see if there are more replies on your thread ... why not log-in and have a quick look around.
*There are other members only boards. But as it depends on how many posts you have made and what group you are in I won't add them here. The only way to see them is to make more posts.
Welcome to music with KatT. Where you can test your music knowledge and see/listen to other member's recommendations
Music Quiz: Score 1 point for each correct answer.
What is the real name of the following artists? (multiple choice)
Artist: Real name and clue:
#1: Sting #A: Eilleen Regina Edwards, Canadian
#2: Alice Cooper #B: Dino Paul Crocetti, passed away in 1995
#3: Elton John #C: John Simon Ritchie, Punk rock
#4: Dean Martin #D: Gordon Matthew Thomas Sumner, 68 years old
#5: Shania Twain #E: Ernest Evans, 78 years old
#6: Freddie Mercury #F: Virginia Patterson Hensley, passed away in a plane crash
#7: Chubby Checker #G: Reginald Kenneth Dwight, from Pinner, Middlesex, London
#8: Sid Vicious #H: McKinley Morganfield, Blues
#9: Patsy Cline #I: Vincent Damon Furnier, 72 years old
#10: Muddy Waters #J: Farrokh Bulsara, passed away at 45
Members recommendations: Each month I ask our members to come up with a music recommendation on a theme. This month it's Sun
Please note that two of the songs are on Deezer but were not available on Spotify. You should also be able to find them on YouTube
If you would like to leave some feedback you can post in the Newsletter thread Here
Well as I write this we have just come off three cracking days of sunshine. Now its tipping down with rumbles of distant thunder. It looks like summer is over again. Still I have managed to break out the barbie a couple of times. I tripped over this recipe while looking for something else and decided to give em a try and they aren't half bad.
So start by by slopping 150g of plain natural yoghurt into a large bowl along with a tablespoon of bog standard shop bought mint sauce (the type in vinegar) and a healthy heaped tablespoon of finely chopped fresh rosemary. Add a good grind of black pepper and some salt, give it a good stir. Hack a couple of skinless chicken breast into big chunks, around 30mm cube and add to the marinade mix. A quick tip, put your chicken into the freezer for 20 minutes so its easier to cut up. It’ll thaw no trouble before you need it. Let the chicken fester at room temperature for around 10 minutes or so.
While the chicken is steeping in the goo, cut a large red onion into 6 wedges and clean a half dozen medium button mushrooms.
Thread the chicken onion and mushrooms onto a couple of skewers alternating each item as you go. If you are using wooden skewers don’t forget to soak them for 20 minutes to stop them from burning when you cook the skewers.
Best done over a nice hot barbie but if its a day like today a hot griddle or a grill will do just nicely. They take around ten to fifteen minutes. Cook until the chicken is just cooked – don’t overcook or the chicken will end up tough and dry.
Serve hot with a nice Greek salad or a cesar salad and a bowl of crisps. Now greedy guts here made four skewers for the two of us. Now although they are really really yummy, they are surprisingly filling - be warned.
To accompany for me its obvious. Its a barbie it has to be an Aperol Spritz. Ok I’ll let you have a cold IPA beer if you must.
To read more recipes or add your own Click here
I m always pleased when members submit photos for use in the newsletter and each month our members can choose 1 image to show on the newsletter and I'm always pleased to add them This months theme is Transport
* All images are property of the member mentioned below the image.
See more members photos Here
Please remember no posts and no log-in for 12 months, your account will be deleted. For more information about this policy See Here!
Talk: Don't keep it to yourself. Share with your friends, family, colleagues and our members here.
Read: You have Psoriasis, try to get some knowledge about your disease, it will make you a better partner for your dermatologist in order to find the best treatment for you.
Get a referral: Don't keep going to a General Practitioner (GP) who can only prescribe creams and ointments, if it's not clearing up ask for a referral to a dermatologist who has a full arsenal of treatments to help.
Tell: Tell your dermatologist all your problems not just about the skin, tell them how it affects your day to day life If you don't they will think you aren't bothered and possibly give you an inferior cheap treatment
Scams: Watch out for scams, there is no cure but you will find a lot of contradictions to that which are designed to empty your wallet and make the scammers rich.
Don't let it get you down: You don't look as bad as you think and anybody that does not like it can go and do the other !!
Appointment support: Take someone to your Dermatologist appointment. They seem to treat you a little differently and having another person allows two sides of the same point to be made. There is also the benefit of extra recall of the consultation.
Applying Topicals: Always apply any topical in the direction of how your hair lies (the grain) it helps avoid more irritation to the skin. Also apply at least half an hour after moisturising for the best absorption.
To see the full list of top tips Or if you have one to share Click Here
Turnedlights poetry corner
Now makes me sigh
To see her dainty white
I chase away and check
The cabbages for tiny eggs
Now a daily fight
Black ants parade
In single file
Up the stalks
And down all day
Marshalling their greenfly troops
I shoot them down
With the soapy spray
And what’s that shine?
Across the grass
That not-straight line
With oily sheen
Towards my lettuce plants
They move by stealth
But by day unseen
The garden has become
A tranquil battleground
The micro war continues
Without really any sound
To put my feet up
And say the fight is won
But slugs and caterpillars know
It’s only just begun..
To read more poems or add your own Click Here
Don't be afraid of being different
Be afraid of being the same as everyone else
To see more thoughts of the day Click Here
This is proving a popular addition to the clubs off topic section
CERTIFIED COVID-19 FREE ZONE
Why not come on over and have a virtual coffee and slice of cake . Here's a place you don't need to keep your distance and can come and sit around one of our virtual tables for a chat
Click Here to enter
Psoriasis Club is self funded, we don't rely on sponsorship or donations. We offer a safe friendly forum and are proactive against spammers, trolls, and cyberbullying. Join us here!
Active Member Count
D Foster with 966
D Foster with 2123
Kat with Nurse: Doctor why did you have me put up a sign saying all patients must wear masks if you aren't going to enforce it!
If you would like to take part in the next round or have a suggestion for a quiz See Here